Targeted Lipidomics Service

Dorawest23 Aug, 2023Health

When you want to study a specific target lipid or lipid class, you can choose targeted lipidomics. Precise method development allows for the inclusion of equal amounts of isotope-labeled or odd-chain internal standards selected from customizable lipid panels. Lipids from each sample are extracted using standardized protocols and analyzed by GC/LC-MS/MS. Analyte concentrations are determined from calibration curves prepared from authentic standards. This approach is especially useful for quantifying lipids present at low levels in samples, such as endogenous bioactive lipids (e.g., prostaglandins, leukotrienes, or endocannabinoids). Standard statistical analysis tools can reveal changing trends in lipid species among experimental groups, which can be visualized with a heat map or other available graphical tools.