Surface Modifiers

Creativebiolabs24 Oct, 2023Technology

Over the decade, research was focused on the discovery of novel therapeutics, and improving the utility of therapeutics that are otherwise limited by suboptimal pharmacokinetic properties like poor absorption, stability, distribution, and elimination. Attempts like chemical modification of drugs or the use of novel drug delivery systems have been proposed to overcome these inconveniences. PEGylation involves modification of the therapeutics by linking one or more polyethylene glycol (PEG) molecules to it. Polyethylene glycol, a polymer of ethylene oxide monomers, being safe and non-toxic, has been approved by FDA for human use.