High-Throughput Screening

Vivian Smith16 Aug, 2023Health

High-throughput screening (HTS) is the iterative testing of different compounds in an assay based on a state-of-the-art, flexible automation platform. A screen is generally considered high throughput if it can assay > 10,000 assays (wells) per day. HTS allows a researcher to quickly conduct millions of tests and to rapidly identify relevant modifier genes, proteins, or compounds involved in a specific biological pathway. The results of these screens typically identify new drug targets or drug activities at a single target and can unveil structure?function relationships in small-molecule ?hits? and functional clustering within biological pathways.