Safety & Efficiency Evaluation

Vivian Smith16 Aug, 2023Health

Safety aspects have become an outstanding issue in the process of drug discovery and development. The International Conference on Harmonization (ICH) has founded a Safety Pharmacology Working Group. Exposure of a drug to the body by pharmacokinetic studies on absorption, distribution, metabolism and excretion has to be investigated at an early stage of development and can contribute to the selection of a compound for development. Toxicology experienced major achievements by the introduction of new methods, e.g., in silico methods, toxicogenomics and toxicoproteomics.