ADME

Vivian Smith16 Aug, 2023Health

ADME (Absorption, Distribution, Metabolism, and Excretion) studies are conducted during the early discovery, lead optimisation, and preclinical development phases. These testing results are to provide information for characterisation and ranking of the compounds based on their properties, and to predict their fate after administration into the human body. At clinical development, the same information related to pharmacokinetics (PK) and pharmacodynamics (PD), is collected to enable and confirm effective use of the candidate drugs.