Cyclobutane sequences do occur in nature
The four carbon atoms in cyclobutane are not coplanar; instead, the rings typically adopt a folded or "pleated" configuration. [2] This means that the C-C-C angle is less than 90?. One of the carbon atoms is at a 25? angle to the plane formed by the other three carbon atoms. In this way, some shadowing interactions are reduced. This configuration is also known as a "butterfly". The equivalent folded conformations are interconverted: Despite the inherent stress, cyclobutane sequences do occur in nature.
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