CuBr was found to be an efficient catalyst for the C–N cross coupling reaction of purine and diaryliodonium salts. 9-Arylpurines were synthesized in excellent yields with short reaction times (2.5 h). The method represents an alternative to the synthesis of 9-arylpurines viaCu(II) catalyzed C–N coupling reaction with arylboronic acids as arylating agents. A highly efficient CuBr-catalyzed coupling of ketones, amines and alkynes (KA2) forming propargylic amines bearing a quaternary carbon center with the broadest scope so far has been developed.
Anna Frozen
Sodovnsite1
Bongvipbar
Dr_raahul_saawant
Btz Software
Dezign Roofing & Exteriors
Joinsmith
Businessticketscom
Fingeng
Vandana Memorial Hospital