Antibody Modification and Conjugation

Jerrycret6814 Sep, 2023Science

As a novel strategy in the therapy various diseases especially oncotherapy, ADCs has received much attention in recent years. It performs targeted therapy owing to the specificity of the monoclonal antibody moiety and the cytotoxicity of the payloads. The majority of ADCs in current oncology clinical trials are canonical IgGs and most of which are built on IgG1 scaffolds.