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Reporter phage assays are very sensitive as they only detect active and viable cells. Another advantage is that the robustness of the assay and the high specificity of the phage, eliminating the need for lengthy sample preparation or purification. There is a large body of literature focusing on the construction and evaluation of many different reporter phages, such as luciferase reporter phage (LRP), green fluorescent protein (GFP) reporter phage, LacZ reporter phage, Ice nucleation (inaW) reporter phage, CelB reporter phage, etc.
Vivian.creativebios@05 May, 2023Science
Creative Biolabs offers membrane protein stable cell line that can overexpress, knockdown, or knockout the target protein of interest to help our clients for membrane protein expression, membrane protein antibody discovery, membrane protein functional studies, membrane protein drug screening etc. Membrane proteins play a key role in cellular function and therapeutic targets, and mediate processes that are critical for the flourishing of biological cells. Membrane-embedded transporters carry ions and bigger solutes across membranes, whereas receptors facilitate communication between the cell and its surroundings and membrane-embedded enzymes catalyze chemical reactions. The difficulty in preparing a sufficient amount of these membrane proteins in order to develop a functional antibody and conduct functional assays is one of the most significant challenges.
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