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Adenovirus Vector Imaging Services

Joannabowie122 Dec, 2022News

Adenoviruses are considered excellent vectors for gene delivery applications and have been increasingly used in in vitro and in vivo research. Creative Biostructure offers iEM Platform, a unique integrated platform for electron microscopy and other microscopy technologies. Based on our wide range of advanced EM technologies and related analysis techniques, researchers can explore the characteristics of adenovirus vectors, including viral structure (e.g., morphology or integrity), and the presence of aggregates and impurities.

iPSCs Morphology

Joannabowie122 Dec, 2022News

Electron microscopy (EM) is a powerful tool for studying the activity, function, properties, and organization of cells, providing insight into the organization and function within cells. The iEM Platform is an advanced and integrated EM platform built by Creative Biostructure. At this unique platform, we can perform detailed and accurate characterization of stem cells to meet the need for large-scale assembly and structural analysis of these cells.

Fragment-based screening in drug discovery

Joannabowie122 Dec, 2022Other

Fragment-based screening (FBS) is a widely utilized strategy for the discovery of lead compounds. Especially in the development of drugs against unconventional targets such as protein-protein interactions (PPIs), FBS has proven to be a viable alternative to high-throughput screening (HTS). Leveraging advanced fragment-based drug design (FBDD) platform, Creative Biostructure provides FBS solutions for customers with hit identification needs, which involve various biophysical methods to determine the exact binding fragments.

IND-enabling Study

Joannabowie122 Dec, 2022Other

With established in vitro/in vivo approaches and our advanced zebrafish screening platform, Creative Biostructure can start from the identified potential lead compounds to study stability, bioavailability, toxicity, efficacy, and other pharmacokinetic parameters to improve their target specificity and potency. Our lead optimization and preclinical development solutions can provide you with better quality leads that have a high probability of success in clinical development.

Coronavirus Cryo-EM 3D Reconstruction

Joannabowie122 Dec, 2022News

The three-dimensional (3D) reconstruction technology of single-particle cryo-electron microscopy (cryo-EM) involves a complex image processing process from two-dimensional (2D) projection images to a 3D reconstruction model. Creative Biostructure currently provides specialized services about single-particle cryo-EM data acquisition and 3D reconstruction of biological macromolecular to promote the progress of coronavirus infection research.

Coronavirus Super-resolution Microscopy

Joannabowie122 Dec, 2022Other

Because most viruses are small (

STD NMR Services

Joannabowie122 Dec, 2022Other

Creative Biostructure is specialized in providing cost-effective contract services to both academia and biotech/pharmaceutical industries in the field of structural biology and membrane protein technologies. We have developed all-in-one, gene-to-structure pipelines for the structure determination of macromolecules of your interest. With a team of experienced professionals, Creative Biostructure is able to solve the structure of many challenging proteins including GPCRs, ion channels, transporters, enzymes and viral targets. We also provide a comprehensive list of products and other related services to facilitate your research in structural biology.

Liposome Production Services

Joannabowie122 Dec, 2022News

Creative Biostructure is specialized in providing cost-effective contract services to both academia and biotech/pharmaceutical industries in the field of structural biology and membrane protein technologies. We have developed all-in-one, gene-to-structure pipelines for the structure determination of macromolecules of your interest. With a team of experienced professionals, Creative Biostructure is able to solve the structure of many challenging proteins including GPCRs, ion channels, transporters, enzymes and viral targets. We also provide a comprehensive list of products and other related services to facilitate your research in structural biology.

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