Online Liposome Extruder

Jessicagenizer27 Apr, 2024Technology

Genizer Online Liposome Extruders can be connected with a sanitary pump or high pressure homogenizer and are temperature controlled, from testing to manufacturing production of pharmaceutical liposomes for anti-cancer drugs. Homogeneous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. Genizer Online Liposome Extruders are designed to generate homogeneous unilamellar liposomes and lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters of defined pore size. The Online Liposome Extruder offers virtually no dead volume, is easy to clean, suitable for sterilization and in compliance with FDA and GMP sanitary standards in pharmaceuticals.

Jacketed Liposome Extruder

Jessicagenizer27 Apr, 2024Technology

The Genizer Jacketed Liposome Extruders is compressed air-driven and temperature-controlled, from testing to manufacturing production of liposome and lipopolyplex, for drug and gene delivery. Homogeneous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. Genizer Jacketed Liposome Extruders are designed to generate homogeneous unilamellar liposomes and Lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters of defined pore size. The process is relatively gentle, exposing the formulation to moderate pressures up to 500 psi at controlled temperatures. The Genizer Jacketed Extruder offers virtually no dead-volume, is easy to clean, suitable for sterilization and in compliance with FDA and GMP sanitary standards in pharmaceuticals.

Liposome HandExtruder

Jessicagenizer27 Apr, 2024Health

The HandExtruder is a manually powered extruder designed for the formulation of 0.25mL-2.0mL liposome and lipopolyplex with small samples. The sample is passed back through the membrane by being pushed back and forth between two syringes. Homogeneous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. The HandExtruder offers minimal dead-volume, is easy to clean and is suitable for sterilization. Temperature control is available

Z-Type Diamond Interaction Chamber

Jessicagenizer27 Apr, 2024Technology

Z-Type Diamond Interaction Chamber (DIXC) is used to produce uniform nanoparticles in a high-pressure homogenizer. The fixed geometry within the Z-Type DIXC is intended to create a uniform processing profile so that all materials will be processed with equal disruptive forces. Single-slotted interaction chambers have a single microchannel and are ideal choices for small batch research, while the multi-slotted interaction chamber comprises multiple microchannels in parallel, which can be used at industrial scales, by increasing the flow rate through the DIXC but with equal processing forces.

Y-Type Diamond Interaction Chamber

Jessicagenizer27 Apr, 2024Technology

Y-Type Diamond Interaction Chamber (DIXC) is used to produce uniform nanoparticles in a high pressure homogenizer. The fixed geometry within the Y-Type DIXC is intended to create a uniform processing profile so that all materials will be processed with equal disruptive forces. Single-slotted interaction chambers have a single microchannel and are ideal choices for small batch research, while the multi-slotted interaction chamber comprises multiple microchannels in parallel, which can be used at industrial scales, by increasing the flow rate through the DIXC but with equal processing forces.

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