Steroid biosynthesis

Dorawest26 Jan, 2024Health

A steroid is an organic compound with four rings arranged in a specific configuration, such as dietary lipid cholesterol, estradiol, testosterone and dexamethasone. Steroid biosynthesis (steroidogenesis) begins with the transfer of free cholesterol from intracellular stores into the inner mitochondrial membrane, where it is transformed into pregnenolone. The conversion of cholesterol to pregnenolone is the rate-limiting step of steroidogenesis and occurs in the single substrate-binding pocket of the cholesterol side-chain cleavage enzyme. Steroids function as important components of cell membranes and many of them are signalling molecules. The malfunction in steroid biosynthesis disrupts the cellular functions and leads to a wide range of human diseases like Lysosomal acid lipase deficiency and Smith-Lemli-Opitz syndrome. In Creative Proteomics, we provide reliable, rapid and cost-effective steroid biosynthesis related analysis service to speed up your research purposes ranging from di