Description MDA-MB-231 cells are a highly invasive, triple-negative human breast cancer cell line widely used in oncology research. Genetically characterized by key mutations in TP53, KRAS, and BRAF, these cells exhibit aggressive growth, strong migratory behavior, and a high metastatic potential. Their mesenchymal-like morphology and ability to model advanced breast cancer make them an essential tool for studying tumor progression, epithelial-to-mesenchymal transition (EMT), and drug resistance.
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