Apoptosis and proinflammatory cytokines

Dorawest26 Apr, 2024Health

Apoptosis plays an important role in the immune system, which is closely related to intracellular homeostasis, T cell aggregation, death of reactive lymphocytes and cytotoxic response of target cells. At present, it has been found that eukaryotic cell apoptosis mainly has the following pathways: 1. Cell receptor-mediated external apoptotic pathways; 2. Internal mitochondrial pathway; 3. B-granase mediated apoptosis pathway; 4. Endoplasmic reticulum stress pathway mediates apoptosis. The detection of cytokines related to apoptosis helps to study apoptosis and the physiological or pathological processes involved. Creative Proteomics can simultaneously quantitatively detect apoptosis and proinflammatory cytokines through a variety of technologies, and provide higher sensitivity and a wider detection range.