When Numbness Doesn’t Work: Exploring Resistance to Local Anesthesia

Kavya Maheshwari31 Oct, 2025Health

Local anesthesia is one of the most important advancements in modern medicine, allowing countless patients to undergo dental procedures, minor surgeries, and diagnostic treatments without experiencing pain. However, for some individuals, this process doesn’t work as expected. They find themselves feeling pain or discomfort even after receiving the recommended dose. This phenomenon, known as resistance to local anesthesia, can be both puzzling and distressing. Understanding why it happens and what can be done about it is crucial for both patients and healthcare professionals.