You can wear makeup before getting Botox, but your provider will clean off the areas where you'll be injected. It's very important for the area to be cleaned and prepped with rubbing alcohol to avoid infection. Is Botox painful? Any injection can hurt, but the needles used for Botox injections are very small, so pain is usually minimal. The area can be numbed with a topical anesthetic cream or cold pack 10-20 minutes before the injections are given, so you may not feel much pain, if any.
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