Kosheeka : Primary Cells For Research16 Jan, 2025Health
Endothelial cells form a one-cell-thick lining of blood vessels, serving as an interface between blood and tissues, with specialized roles based on their tissue origin. In kidneys, fenestrated endothelium aids in filtration and fluid balance, while continuous endothelium protects organs like the brain with its tight barrier. Discontinuous endothelium, found in the liver and spleen, enables the transport of larger molecules and cells. Cultured in vitro, endothelial cells display a cobblestone appearance and express key markers like CD31, Factor VIII, and LDL uptake.
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