Healtcareresearch09 Dec, 2021Health
Vildagliptin is an antihyperglycemic medication that inhibits the dipeptidyl peptidase-4 (DPP-4) enzyme selectively. It is used to treat type 2 diabetes mellitus, which is characterized by impaired GLP-1 production and insulinotropic effects. DPP-4 is inhibited. Glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), both incretin hormones that stimulate insulin production and control blood glucose levels, are protected from breakdown by vildagliptin. GLP-1 and GIP levels are elevated, which leads to better glycemic control. Vildagliptin has been shown in clinical studies to have a minimal risk of hypoglycemia.
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