Precision health focuses on creating tailored health and wellness strategies by integrating individual biological, environmental, and lifestyle factors. Rather than taking a one-size-fits-all approach, precision medicine considers unique genetic, epigenomic, microbiome, and metabolic profiles to determine disease predisposition, risks and recommend targeted interventions. This level of multi-OMICS specificity not only helps guide diagnosis and treatment but also provides better understanding factors involved in longevity and aging. This determination of health span; the number of years lived in good health, can effectively improve our understanding of the differences between chronological and biological age.