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Treatment of acute pain, primary dysmenorrhea. Nimesil should only be used as a second-line drug. The decision to prescribe nimesulide should be made on the basis of an assessment of all risks for a particular patient.Treatment of acute pain, primary dysmenorrhea. Nimesil should only be used as a second-line drug. The decision to prescribe nimesulide should be made on the basis of an assessment of all risks for a particular patient.Treatment of acute pain, primary dysmenorrhea. Nimesil should only be used as a second-line drug. The decision to prescribe nimesulide should be made on the basis of an assessment of all risks for a particular patient.