RIP-Seq

Kiko23 Jan, 2024Health

RIP-Seq maps the sites at which proteins are bound to the RNA within RNA-protein complexes. RNA immunoprecipitation (RIP) implies the purification of RNA–protein interactions in native conditions by using a protein-specific antibody to map the RBP of interest. The advent of sequencing technologies, coupled to various RIP chemistries, has enabled the simultaneous detection of thousand of bound transcripts (mRNAs, non-coding RNAs or viral RNAs) in a single experiment. CD genomics provides RIPed RNA sequencing to obtain insights into not just the well-established processes such as transcription, splicing and translation, but also in newer fields such as RNA interference and gene regulation by non-coding RNAs.