Phage Display

Jerrycret6823 Oct, 2023Technology

Phage display is a powerful library methodology for high-throughput screening of molecular interactions. The general procedure initiates from the construction of a library with peptide or antibody variants. By inserting its encoding gene into a phage coat protein gene, a protein (protein fragment or peptide) can be displayed on the surface of a phage particle, with its genetic material resides within the phage particle. This connection between genotype and phenotype allows further enrichment of specific phage.