The market for papain is growing due to its health benefits. Papain is a naturally occurring proteolytic enzyme, and it is being used more and more in place of chemically derived proteolytic enzymes. In addition, papain is also used in pharmaceuticals, in a gel called Papacarie. This gel is used for various purposes, including tooth whitening, cleaning chronic wounds, and dissolving cells in cell culture preparations. The food & beverage and pharmaceuticals sectors are two of the main industries that consume papain. However, due to the recent production stoppages and disruptions in the supply chain, the demand for papain has declined. Additionally, the manufacturing industries of textile & detergent, personal care & cosmetics are completely closed due to the lockdown, further reducing the demand for papain. Animal feed industries are also reducing their production, which also contributes to the decline in the papain market Size.