Nitisinone: Usage

Comparator Drug Clinical Trial06 Jul, 2023Health

There were no patients aged 65 and up in the nitisinone clinical trials to examine if they responded differently than younger people. HT-1 is currently classified as a pediatric disease. There have been no pharmacokinetic studies of nitisinone in the elderly. In general, dosing for an elderly patient should be conservative, often starting at the low end of the dosing range, reflecting the higher prevalence of decreased hepatic, renal, or cardiac function, as well as concomitant disease or other drug therapy in this patient population. For additional information on the use of Nitisinone 2 mg in older people, please contact us.