Nitisinone: Dosage

Comparator Drug Clinical Trial15 Jun, 2023Health

The suggested dosage ranges between 1 and 2 mg/kg twice daily. First-time users are given 1 mg/kg/day in the morning and evening. A medical provider should administer the nitisinone medication experienced in treating HT-1 patients. Each patient's nitisinone dosage can be adjusted. If erythrocyte PBG-synthase activity, urine 5-ALA, and urine succinylacetone do not return to normal after one month of treatment, the dose of Nitisinone may be increased to 1.5 mg/kg/day. Suppose erythrocyte PBG-synthase activity, urine 5-ALA, and succinylacetone remain elevated after three months in individuals taking 1.5 mg/kg/day. In that case, the dose may be increased to a maximum of 2 mg/kg/day. The drug might be available at many marketplaces, but it is mandatory to buy the drug from authorized Nitisinone distributors from India, such as The Indian Pharma.