Acute myeloid leukaemia (AML) can develop from the chronic myeloproliferative neoplasm known as myelofibrosis, which is characterised by bone marrow fibrosis and abnormal blood cell generation. This metamorphosis is an uncommon but significant occurrence that presents particular difficulties in patient diagnosis and care. For effective tactics to stop or control this destructive advancement, it is essential to comprehend the elements causing this transition.
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