isothermal titration calorimetry data analysis

Melissageorge122 Dec, 2022Other

Isothermal titration calorimetry (ITC) is one of the physical techniques used to directly measure the reaction process between biomolecules. It is an analytical method for determining the contact between ligands and macromolecules at a constant temperature. ITC uses the thermodynamic principle that the combination of two molecules will cause the generation or absorption of heat to determine the binding affinity, stoichiometry, entropy, and enthalpy of the binding reaction in the solution.