An STD, often known as a sexually transmitted infection (STI), is a dangerous ailment that can develop after unprotected sex. Itching and burning around the vaginal area are common STD symptoms. The good news is that STD therapy (typically antibiotics) can be effective in curing the infection. You can contract an STI/STD once more. When having any form of sex, always be sure to use a condom or dental dam. What are the Sexually Transmitted Diseases (STDs) Treatment? There are many STDs that can be treated by antibiotics. Depending on the medication, you will be administered an injection or oral intake (through the mouth).