The pain relief effect of Tapentadol is realized about 30 minutes after administration in tablet form. Inform your doctor if you start to experience side effects from Tapentadol and avoid any medications that may interact with your prescription, including alcohol, while it remains in your system. If you?re unsure about the safety of taking other medications or drinking alcohol after taking your prescription of Tapentadol, bring this up to your doctor. There are many factors that influence how long Tapentadol will stay in your system after the last dose.
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