Hepatitis C Drug Candidate Is Effective Against SARS-CoV-2
Multiple studies are carried out to explore the benefits of antiviral drugs, especially hepatitis C virus direct-acting antivirals (HCV DAAs) to treat COVID-19. This study was conducted to evaluate the anti-SARS-CoV-2 effects of asunaprevir (a protease inhibitor), daclatasvir (an NS5A inhibitor) and sofosbuvir (an RNA polymerase inhibitor). Vero E6, Calu-3, Huh7.5, and HEK293T cell lines were used for testing the antiviral activity of the drugs against SARS-CoV-2 in vitro.
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