The fully liquid vaccine is currently a component of national immunization schedules in at least 65 countries eligible to receive vaccines through the GAVI Alliance. Corynebacterium diphteriae is a bacterium which can cause myocarditis (inflammation of the heart muscle), inflammation of nerves and kidney problems. It is transmitted by contact, by contaminated objects or through the air. According to World Health Organization (WHO) data, incidence of diphtheria is on the rise: countries reported more than 7,000 cases in 2016, and almost 17,000 in 2018. Death occurs in 5% to 10% of those infected, mainly in children under 5 years of age.
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