Gefitinib: Treatment of non-small cell lung cancer

Marykudro22 Mar, 2022Health

Gefitinib is the active ingredient in medicine and inactive ingredients such as lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, povidone, sodium lauryl sulfate, and magnesium stearate. Gefitinib reversibly inhibits the kinase activity of wild-type and specific activating mutations of EGFR, preventing autophosphorylation of tyrosine residues associated with the receptor, thereby inhibiting further downstream signaling and blocking EGFR-dependent proliferation. Its binding affinity for EGFR exon 19 deletion or exon 21 point mutation L858R mutations is higher than its affinity for the wild-type EGFR. Gefitinib tablets come in 250 mg to administer orally. Gefitinib price is reasonable among several generic medicine suppliers in India. Ikris Pharma Network is the certified supplier of pharmaceutical drugs, supplying medicines across the world for more than 7 years.