Product lifecycle management (PLM) is a crucial business component for companies operating in manufacturing and supply chain industries to channelize their sales cycle. Developing and implementing a PLM software enables businesses to steer clear of the challenges associated with supply chain management. It is, therefore, critical to have your ERP systems integrated with a PLM software to efficiently manage supply chain activities. The ERP-PLM integration is even more important for small-scale manufacturers who are normally competing at many different levels. It would not only streamline their production processes but would also help them align their operations in accordance with the latest quality standards. Here, we shed light on the importance of ERP-PLM integration for small and medium-sized manufacturing companies. At the same time, we highlight different ways that PLM integration helps streamline operations associated with supply chain management.