Carvedilol is a non-selective adrenergic blocker used in clinically stable individuals to treat heart failure with reduced ejection fraction (HFrEF), hypertension, and left ventricular dysfunction after a myocardial infarction (MI). Carvedilol's off-label uses include stable angina, atrial fibrillation, cirrhotic esophageal variceal hemorrhage prevention, and ventricular arrhythmias. This exercise examines the mechanism of action, adverse event profile, toxicity, dosage, pharmacodynamics, and monitoring of carvedilol, which is important for clinicians and other members of the inter-professional team in order to use carvedilol appropriately for the specified conditions.