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Acetaminophen (commonly referred to as paracetamol) and hydrocodone are both active components in the brand-name drug Vicodin. Acetaminophen is a non-opioid analgesic and fever reducer, whereas hydrocodone is an opioid painkiller. Most often, doctors will prescribe Vicodin to treat moderate to severe pain. It reduces the experience of pain by attaching to opioid receptors in the brain and spinal cord. On the other side, acetaminophen can assist lower temperature while also enhancing the pain-relieving effects of hydrocodone.
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