ABSTRAL Fentanyl sublingual tablets is a solid formulation of fentanyl citrate, a mighty opioid analgesic supposed for oral sublingual management. ABSTRAL is formulated as a white tablet to be had in six strengths, distinguishable by means of the shape of the tablet and by de-bossing on the pill floor. active component: Fentanyl citrate, USP is N-(1-Phenethyl-4-piperidyl) propionanilide citrate (1:1). Fentanyl is a notably lipophilic compound (octanol-water partition coefficient at pH 7.4 is 816:1) that is freely soluble in natural solvents and sparingly soluble in water (1:40). The molecular weight of the loose base is 336.5 (the citrate salt is 528.6). The pKa of the tertiary nitrogens are 7.three and eight.4. All pill strengths are expressed as the amount of fentanyl unfastened base, e.g., the 800 mcg energy pill contains 800 mcg of fentanyl loose base.
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