Even as the world awaits a vaccine to tackle the global pandemic instigated by the novel coronavirus, there are over 22,000 known medical conditions many of which are treatable with drugs, devices, biologics, or other therapies. About 7000-9000 of these conditions are considered rare disorders because taken one at a time, they affect fewer than 200,000 Americans. About 80% of these diseases are genetic in origin, 50% of them affect children and 30% of them do not live to see their 5th birthday. Taken together, rare diseases affect an estimated 350 Million people worldwide. That’s approximately the same number of patients living with Diabetes worldwide.