Even though both methods highly effective at preventing HIV among men who have sex with men and transgender women, it is found that Long-acting injectable form of HIV prevention outperforms daily pill. A pre-exposure prophylaxis (PrEP) regimen containing an investigational long-acting form of the HIV drug cabotegravir injected once every 8 weeks was more effective than daily oral Truvada at preventing HIV acquisition among cisgender men in a clinical trial sponsored by the National Institutes of Health.
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