The gut microbiota – commonly referred to as your microbiome – plays a key role in your mental health through its constant communication with the brain via the vagus nerve. Key neurotransmitters targeted by medications for improving symptoms of depression – serotonin and dopamine – are actually produced in the greatest concentrations in the gut (not the brain). This gut:axis is highlighted by research showing that if you are overweight, you’re at much greater risk of poor zonulin function, a key molecule that regulates gut permeability.
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