How do I contact Expedia's customer service for help with a booking? To contact Expedia's customer service for help with a booking, you can call their support number at +1-(800)-205-9716). This number is available for inquiries related to flights, hotels, car rentals, and vacation packages. Additionally, you can access their support through the "Help" section on the Expedia website, where you can find options for live chat or submitting a query through an online form. When contacting customer service, have your booking information ready, such as your itinerary number, to expedite the process. The support team is available to assist with booking changes, cancellations, refunds, and any other issues you may encounter.